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Explanation of analyzes

RFMC during pregnancy - what is it? The value of the norm, increased RNMC

During pregnancy, genetic and acquired diseases of blood and circulatory system become aggravated. One of the main reasons is the appearance of the third cycle of circulation - uteroplacental and placental-placental blood flow. The woman's organism is forced to reorganize and in a short period of time learn how to function in new conditions.

This leads to an increase in blood viscosity, an increase in the number of platelets, a change in the indices of the products of decomposition of thrombi and the level of RMKM-a soluble fibrin-monomer complex.

If the problem is not detected on time and the blood-thinning therapy is not prescribed, then the expectant mother seriously risks losing the baby - he can both die in utero and be born prematurely.


RFMK - what is it?

RFMC in pregnancy

RFMC is an indicator of the level of fibrin degradation products in the blood, which is responsible for the formation of thrombi within the vessels of a pregnant woman. Normally, it rises slightly during pregnancy, but in patients with thrombophilia and blood clotting disorders that have a different etiology, RFMC parameters can reach critical levels.

This condition requires prompt medical intervention.

Analysis for a soluble fibrin-monomer complex is not performed for all pregnant women, but only for those who have certain indications for such a survey.

Thrombophilia is a genetic disease characterized by a high risk of thrombosis and a habitual miscarriage of pregnancy. The analysis is appointed by the geneticist, then the gynecologist thinks through the therapy in such a way as to increase the chances of the future mother to deliver the baby to 35 to 36 weeks.

In the presence of this hereditary disease, the determination of the level of RFMC is an obligatory procedure that is performed several times during pregnancy.

DIC-syndrome (disseminated blood clotting in blood vessels) - involves the violation of hemostasis, which is characterized by the formation of a large number of microclots in the blood. The disease has several stages of development, but if it is found in a pregnant woman, then throughout the 9 months the doctor will monitor the RFMK parameters.

Identified thrombosis - the condition is very dangerous, so an obstetrician-gynecologist will be forced to prescribe an analysis on RFMC often to save the life not only of the baby, but of his mother.

Norms of RFMC during pregnancy in trimester

Norms of RFMC during pregnancy in trimester

Despite the fact that bearing a child assumes a slight increase in the indices of thrombinemia markers, there are certain norms of RFMC during pregnancy that do not require correction with medicinal preparations.

  • I trimester - the indices are practically the same as those of a healthy non-pregnant woman. This means that as a result of the analysis thrombinemia markers will not be more than 5.5 mg 100 ml (in patients who are not pregnant, a normal result is 5 mg 100 ml). The placenta has not yet formed at this time, therefore, there is practically no increase in blood clotting.
  • II trimester - the indices become larger and amount to 6.5 mg 100 ml. RFMK is elevated and the reason for this is quite natural - the placenta ripens by the 16th week and begins to function in full, and along with it the utero-placental and fruit-placental blood flows are included. This leads to an increase in the viscosity of the blood.
  • III trimester - RFMC indicators reach the level of 7.5 mg 100ml. In comparison with the norm for non-pregnant women, the marker of thrombinemia has a pronounced tendency to increase. This process is associated with aging of the placenta. Another indicator of blood viscosity, d-dimer , behaves as well as RFMC - gradually increases by the end of the period of bearing of the child.

The doctor should evaluate the results of the analysis, because different laboratories may have completely different units of measurement for this marker.

RFMK during pregnancy is increased - what to do?

RFMC during pregnancy is elevated

Deviations from the norm are those indicators that are much higher than the values ​​provided for each trimester of pregnancy. And, to monitor the values ​​of the thrombinemia marker need in dynamics.

If the gynecologist notes that RFMK is high for several weeks and the therapy prescribed by him does not give any result, he sends the patient to the genetics and hematologist for advice and recommendations for further treatment.

Especially should alert, if the viscosity of the blood increased sharply, within a short period of time and began to exceed the allowable rate several times.

In this case, the gynecologist is obliged to place the patient in a hospital to provide emergency assistance, because a sudden rapid increase in RFMC threatens not only the baby, but also the mother's life.

The tactics of treating a high level of blood viscosity

Therapy should begin no later than 9 weeks of pregnancy and continue until the end of the period. The treatment uses a blood-thinning medication, consumed orally or by injection. If the increase in RFMK is stable, then therapy is not interrupted. The doctor only changes medicines, but the treatment course follows one after another.

  • Curantil - is prescribed in tablets, which are prescribed to take 2-3 times a day for 3 weeks.
  • Actovegin is usually prescribed in injections, with a course of 10 to 15 injections. It takes a break for 4 to 6 weeks, and then the drug is administered again. If the situation with RFMK is not critical, then Actovegin is prescribed in tablets. If it is necessary to reduce marker indicators urgently, then the drug is dripped intravenously.
  • Flebodia - is prescribed in tablets, as a rule, 1-2 times a day for 1 dragee. The doctor can alternate the drug with Currantil, but in no case do not combine their reception.
  • Folic acid - a positive effect on the destruction of blood clots, so it is prescribed to drink throughout the pregnancy without interruption.

How is biological material taken for analysis?

To evaluate the indices of thrombinemia markers, blood is taken from the vein. The analysis itself is done quite quickly - no more than 3 days. Some laboratories work more quickly and can send the results of the study by e-mail on the same day that the blood was taken.

To obtain the correct picture of RFMK, it is necessary to observe the following requirements:

  • The clinic should appear on an empty stomach, the last meal should be at least 8-9 hours before the procedure.
  • The day before the analysis, it is necessary to exclude the use of hemorrhagic drugs.
  • During the day, refrain from stressful situations and physical overwork.

Ignoring even one of these conditions can significantly distort the analysis data. As a result, the attending physician will not be able to adequately assess the patient's clotting state.

At all desire to care of the future kid it is necessary to understand, that the question on what to do at the raised or increased level RMON during pregnancy, the doctor should consider. Self-medication can lead to sad results, aggravating the situation to a critical one.


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