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Hormonal failure in women: causes, signs, symptoms and treatment

Hormones largely determine the functioning of the female reproductive system. They are in such close relationship that the lack or excess of one of them leads to the fact that after it begins the wrong production of other hormones.

As a result, menstrual irregularities begin, which are difficult to correct. The process of restoring the endocrine system takes a long time, and in some cases it is completely impossible.

There may be two reasons for this: misuse of hormonal drugs or congenital dysfunction of the organs responsible for the production of hormones.

If in the first case there is the possibility of a complete recovery of the endocrine system, then in the second only treatment regimens that will temporarily correct the incorrect production of hormones can help.


Woman's endocrine system - how it works

What is a hormonal failure

What is a hormonal failure?

The failure of the hormonal system can begin at any age, but most often it affects either teenage girls or women during menopause, when the endocrine system undergoes dramatic changes.

Hormones in the female body are produced by certain glands, which in medical science are called the glandular apparatus.

Some of these glands are directly related to the functioning of the reproductive system of a woman:

– мозговой придаток, расположен в нижней поверхности мозга. The pituitary gland is a brain appendage located in the lower surface of the brain. Responsible for the production of prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), oxytocin.

– расположена в области шеи, над гортанью. The thyroid gland is located in the neck, above the larynx. Responsible for the production of thyroxin, which affects the growth of the endometrium in the uterus.

– являются парными железами, которые располагаются над почками. Adrenal glands are paired glands that are located above the kidneys. They are responsible for the production of progesterone, a number of androgens and a small amount of estrogen.

– парные железы, расположенные в полости малого таза. The ovaries are paired glands located in the pelvic cavity. Responsible for the production of estrogen, weak androgens and progesterone.

If, in older women, endocrine system dysfunction occurs due to the consumption of ovary stocks and the extinction of the ability to bear children, the hormonal failure in girls indicates, on the contrary, that the body is growing up and preparing for reproductive functions.

Hormones that affect the female reproductive system

Causes of hormonal failure Estrogens - the common name of the three hormones: estriol, estradiol and estrone. Are produced by the ovaries and partially by the adrenal glands. They are hormones of the first phase of the menstrual cycle.

Prolactin - affects the formation of milk in the mammary glands. Helps reduce estrogen levels and inhibits ovulation during breastfeeding.

Follicle-stimulating hormone - produced by the pituitary and hypothalamus. It accelerates the growth of follicles in the ovaries in the first phase of the menstrual cycle. It affects the production of estrogen.

Luteinizing hormone - is produced by the pituitary gland, stimulates the production of estrogen, provokes the rupture of the capsule of the dominant follicle and the release of a ripe egg cell from it. It is closely related to the production of follicle-stimulating hormone.

Testosterone is a male sex hormone. In women, a small amount is produced by the adrenal cortex and ovaries. Promotes breast augmentation during pregnancy.

Progesterone is a hormone of the corpus luteum, which is formed after breaking the capsule of a dominant follicle during ovulation. In addition, it is produced in large quantities by the ovaries and placenta if the woman is pregnant.

These are the main hormones that more affect the menstrual cycle than all others, which are also produced by the endocrine glands.

7 causes of hormonal failure

Hormonal drugs can cause a violation

Hormonal drugs can cause a violation

Improper hormone production can be both congenital and acquired during life. Treatment for this problem will depend on what caused the endocrine system to malfunction:

Прием оральных контрацептивов. 1) Acceptance of oral contraceptives. Despite the fact that some gynecologists believe that oral contraceptives normalize the hormones of a woman, this is not always the case. After the abolition of pills in some patients, the endocrine system can not establish its functions.

Прием препаратов для экстренной контрацепции. 2) Acceptance of drugs for emergency contraception. It leads to a strong hormone surge, after which the menstrual cycle may not return to normal for a long time.

Несанкционированный прием прочих гормональных препаратов. 3) Unauthorized use of other hormonal drugs. Funds regulating the work of the endocrine system should be prescribed by a doctor of the appropriate profile. Even if the test results show a deviation from the norm of any hormone, then it is not desirable to select medicines for correction by yourself. Only an endocrinologist can prescribe an adequate treatment regimen.

Нарушение функций эндокринных желез. 4) Dysfunction of the endocrine glands. It can occur as a result of their diseases, and as a result of anomalies of their development.

Возрастные физиологические изменения. 5) Age-related physiological changes. It implies puberty and menopause — two periods in a woman’s life in which the most fundamental restructuring of the endocrine system is noted.

Искусственное прерывание беременности. 6) Artificial abortion. Sudden cessation of production of hCG entails a violation of the production of estrogen, progesterone and testosterone. Both drug and surgical abortions equally affect the endocrine system.

Длительные стрессовые состояния. 7) Prolonged stressful conditions. Affect the suppression of the production of the hormone oxytocin. Lowering oxytocin has an effect on prolactin production.

Pregnancy can also be a cause of hormonal disruption, but in this case, the body has programmed natural ways to normalize the functioning of the endocrine glands, which are activated after childbirth.

Symptoms of hormonal failure in women

Hair growth and sudden mood swings are symptoms of hormonal imbalance

Hair growth and sudden mood swings are symptoms of hormonal imbalance

Hormonal disorders never pass without consequences. Depending on which of the endocrine glands is not functioning properly, a woman has certain symptoms of hormonal disruption.

By symptom in medicine is meant the totality of the manifestations of the disease that the patient himself notices. In this case, the symptoms will be the following:

  1. Violation of the duration of the menstrual cycle;
  2. Intermenstrual bleeding ;
  3. Abundant menstruation ;
  4. Excessive body hair growth;
  5. Excretion of milk from the mammary glands in the absence of breastfeeding;
  6. Frequent mood swings;
  7. Weight gain with relatively moderate food intake;
  8. Hair loss;
  9. Decreased libido.

These symptoms should alert and become a reason to visit the endocrinologist.

Signs of endocrine disruption

Signs of women Under the sign in medicine refers to the totality of the manifestations of the disease, which observes the doctor. He is a clinical picture of the disease, relying not only on the data of medical research, but also on the complaints of the patient.

As signs of hormonal disruption in women, the following can be highlighted:

  • The shortening or lengthening of the first or second phase of the cycle;
  • Lack of ovulation;
  • Ovarian cysts;
  • Cysts of the yellow body;
  • Thin or too thick endometrium;
  • The presence of fibroids;
  • Violation of the process of maturation of follicles (regression of the dominant follicle, follicular cyst);
  • A large number of antral follicles in one ovary, not exceeding 8-9 mm in diameter (MFN);
  • A large number of follicles in one ovary, which are larger than 9 mm in diameter, but still smaller than the dominant follicle (PCOS).

Hormonal failure during pregnancy

The body undergoes changes after conception. From the day the fertilized egg is implanted in one of the walls of the uterus, the production of the hCG hormone begins. Increasing its concentration in the blood provokes a change in the amount of production of other hormones.

The endocrine system is forced to adapt to the changes that have occurred in the body, but hormonal disruption during pregnancy is a natural process that is necessary for successful childbearing.

But there are violations that can lead to the threat of miscarriage:

  1. Lack of progesterone.
  2. Excess testosterone.
  3. Lack of estrogen.

These are the three main hormonal disorders that pregnant women face most often. For their correction, the gynecologist will prescribe medication therapy.

The consequences of improper functioning of the endocrine system

Hormonal failure is a factor that adversely affects a woman’s health. It is not only about the violation of childbearing functions, but also about the general deterioration of health.

The lack or excess of certain hormones, in the absence of timely treatment, can lead to serious consequences, including:

  • Infertility;
  • Miscarriage of pregnancy;
  • Obesity;
  • The occurrence of cancer;
  • Reduced immunity;
  • High fatigue;
  • The formation of benign tumors;
  • Diabetes;
  • Osteoporosis;
  • Decreased sexual activity.

If the cause of the hormonal imbalance lies in the improper functioning of the endocrine glands, which was observed from birth, it requires constant observation of the endocrinologist and a systematic correction of the production of a hormone.

Treatment of hormonal failure in women

Treatment of hormonal failure in women

The treatment regimen will depend on which hormone deviates from the normal values. Sometimes there are problems with the production of any one hormone, but most often a blood test indicates the presence of problems with several hormones at once.

Each doctor has his own views on the methods of treatment, but gynecologists and endocrinologists can be divided into two categories: the former prefer to prescribe oral contraceptives as a therapy, and the latter prefer to regulate each hormone with separate drugs.

Correction of hormonal failure with oral contraceptives

To normalize the production of hormones can be prescribed such drugs as Yarin, Diane 35, Jess, Lindinet. On the one hand, the doctor is comfortable: you do not need to select a special treatment regimen - in tablets, all synthetic analogues of hormones are pre-distributed on the days of the cycle.

On the other hand, such a correction is fraught with negative consequences:

  • Intolerance to oral contraceptives, expressed in daily severe nausea and vomiting.
  • Unplanned pregnancy after the abolition of pills. And, due to the rebound effect, it may turn out that a woman bears a double or a triplet.
  • Strengthening signs of hormonal imbalance after the cancellation of oral contraceptives

Correction of hormonal failure with the help of an individual selection of hormonal drugs

Such a treatment regimen is more difficult. There is a need to use several hormonal agents at once, therefore, the gynecologist-endocrinologist must choose drugs in such a way as not to provoke a violation of the production of other hormones that are normal.

  • Excess testosterone - Dexamethasone, Tsiproteron, Metipred is used for treatment.
  • Progesterone Deficiency - Duphaston, Utrogestan is used to normalize indicators.
  • Lack of estrogen - corrected with the help of Divigel, Premarin, Proginova.
  • Excess estrogen - treated with Clomiphen, Tamoxifen.

These are just a few examples of solving problems with the production of certain hormones. In fact, there may be much more, and the endocrinologist should be a specific treatment regimen. . For the correction of hormonal background, herbs are also used, but they should be taken only on the recommendation of a doctor .

As a preventive measure, it can be advised not to take hormonal drugs without permission, without an appointment and control of a doctor. Once a year you need to donate blood for the analysis of the main female hormones and in case of deviation of one or several of them from the normal values ​​refer to an endocrinologist or gynecologist.


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