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Diffuse changes in the liver, parenchymi: signs, causes, treatment

The liver in the human body plays the role of a kind of filter through which blood passes and is cleansed of toxins. The nature of this gland is created so that the liver cells are devoid of nerve endings. That is why the liver tissue itself can not hurt.

Most diseases in the liver are asymptomatic. This happens until the size of the liver becomes greatly enlarged. The enlarged organ stretches the capsule, which covers the liver, acting on the numerous nerve endings located in it.

Then the person begins to experience pain in the liver ( right hypochondrium ), but it may take years. For a long time you may not know that the liver is suffering and requires help. The organ's compensatory abilities are huge. Often, pathological changes are detected by chance during ultrasound examination of other organs.


Diffuse liver changes, what is it?

Diffuse changes in the liver

The concept of "diffuse changes" is not a diagnosis and does not reveal the essence of the process that develops in the body. This term is used by diagnosticians during ultrasound diagnostics.

What it is? Diffuse changes in the liver is a change in the structure of the tissue that is distributed relatively evenly throughout the organ. So many diseases can manifest. The doctor conducting the ultrasound - the study sees these changes in the form of increasing or reducing the echogenicity of the liver tissue.

The conclusion made after the ultrasound is the starting point for additional methods of examining the liver and detecting a particular disease.

The cause of diffuse changes in the liver can be diseases that affect the hepatic parenchyma. These can be inflammatory diseases of the liver of viral nature (hepatitis), fatty degeneration of hepatocytes due to alcohol intoxication, in case of poisoning, with long-term use of potent drugs.

The structure of the liver can be disrupted due to autoimmune diseases, with cirrhosis of the liver of any origin, infiltrating tumors.

Also, changes in the liver tissue can occur when the diet is not followed and when excessive fatty, fried foods are consumed. Less often, the changes are innate.

Signs of diffuse changes in the liver

As mentioned above, liver disease for a long time may be asymptomatic. The liver can give signs, but rarely are they properly evaluated.

Symptoms of diffuse changes in the liver can clinically manifest as heaviness in the right hypochondrium, headache, fatigue, abnormal stool, loss of appetite, a bitter taste in the mouth, and bad breath.

The appearance may also indicate a malfunction in the liver: the skin becomes unhealthy in color with a yellow or brown tint, in some cases there is a loss of body weight.

Diffuse changes in the liver during ultrasound diagnosis

Diffuse changes in the liver during ultrasound diagnosis

Ultrasound is considered one of the most accessible and non-invasive methods of liver examination. The ultrasound machine is available in every medical diagnostic facility.

A good method and the fact that does not require lengthy preparation. The patient needs only to follow a diet for a couple of days before the study, aimed at reducing gas formation in the intestine. Gas bubbles distort the real picture and interfere with the viewing of organs.

The study should be conducted by a doctor with an education and a certificate in this narrow specialty.

Consider what diffuse changes a doctor can detect during a liver ultrasound.

Healthy liver

If a person's liver is completely healthy, then with ultrasound diagnostics it has normal dimensions, smooth edges. The liver echo is normal should be of weak intensity. In the locations of vessels, echo is reduced.

The structure should be uniform throughout the body with a fine grain size characteristic of the liver.

Changes in fatty liver hepatosis

Fatty hepatosis is a condition in which fat is deposited in the cytoplasm of hepatocytes. This is very common in alcohol intoxication, obesity, and diabetes.

Diffuse fatty changes in the liver cells on ultrasound are recorded as an increase in echo over the entire area of ​​the organ. The liver is enlarged and has rounded edges. Sometimes diffuse changes in the liver are combined with changes in the pancreas and spleen.

If left without treatment fatty hepatosis, then in the future it can develop into cirrhosis of the liver.

Diffuse changes in the liver parenchyma

Diffuse changes in the liver parenchyma

In cirrhosis, the liver tissue grows with connective tissue that forms the false lobules of the liver. The liver becomes dense, with an uneven surface, hepatocytes of different sizes - partly compensatory enlarged, some in a state of atrophy. At the site of the dead hepatocytes grows coarse connective tissue.

On ultrasound revealed the following:

  1. There is an increase in echo. The liver tissue has a mosaic look.
  2. The size of the body is increased (in the last stage of the disease, on the contrary, reduced).
  3. The surface of the liver is knobby due to the formation of nodes.
  4. The vascular pattern changes: the portal vein with a thickened wall, numerous collaterals are found.

Ultrasound signs of hepatitis

Hepatitis is an inflammatory change in the liver caused by viruses, alcohol, toxins, etc. Hepatitis can be acute and chronic. Ultrasonic signs of hepatitis are non-specific. The doctor has the right to make a diagnosis only after conducting the appropriate tests.

In acute and chronic hepatitis, echo amplification is noted. The liver is enlarged. The parenchyma may be homogeneous or with foci of heterogeneity.

Due to the fact that it is difficult to make an accurate diagnosis based on the results of ultrasound alone, the doctor who conducted the study only points out the nature of the changes seen: diffuse or focal changes in the liver tissue.

In the future, the patient must undergo a more detailed diagnosis to clarify the diagnosis.

Treatment of diffuse liver changes

Treatment of diffuse liver changes

Before you think about how to treat changes in liver tissue, the doctor must figure out which disease has led to these changes. For this, he must conduct additional analyzes and research. Only after setting a clinical diagnosis, treatment is prescribed.

Whether treatment will be successful depends on the nature of the disease and the degree of liver tissue changes. Moderate diffuse changes in the liver tissue are detected in a large number of people. More often, their appearance is associated with improper diet, alcohol intake, smoking, poor ecology.

In most cases, diffuse changes respond well to treatment. For example, diffuse changes in the parenchyma of the liver, occurring as fatty hepatosis can be eliminated.

Suffice it to completely eliminate the cause of obesity of hepatocytes. Studies have shown that fatty degeneration of hepatocytes caused by alcohol intoxication, with the exclusion of the provoking factor, is able to reverse development. After 6 months, hepatocytes containing fatty drops in their cytoplasm become completely healthy.

This applies not only to alcohol, but to liver obesity due to malnutrition. It is necessary to stick to a diet so that the fat stops being deposited in the liver cells.

There are situations when a patient has to take complex drugs for a long time, which have a toxic effect on hepatocytes. Often this is observed in the treatment of severe diseases that require long-term therapy, for example, in tuberculosis or tumor processes.

In this case, the appearance of changes in the liver tissue is inevitable. To prevent liver damage, the doctor prescribes drugs of hepatoprotective action. Drugs of this group are capable of forming a protective shell on the surface of the liver cell, protecting it from toxic damage.

Also effective will be treatment for viral diseases, it is enough to undergo a course of antiviral therapy. It is important to consult a doctor when changes in tissue have not yet reached far, and the structure of the liver has not undergone deformations.

It is clear that in case of cirrhosis or a diffuse tumor process it is rather difficult and practically impossible to restore the previous structure to the liver. But with a timely visit to the doctor, you can stop the pathological process, and save the life of the patient.

Do not be afraid, seeing in conclusion the phrase "diffuse changes". Sometimes it even benefits the patient. Thus, when weak or moderately pronounced changes are detected, there is a chance for a complete cure and prevention of the development of severe liver diseases with a pronounced violation of the structure and function of the organ.


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