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Why is Bioparox banned in Russia? Reasons and analogues for replacement

Bioparox banned to use around the world!

Popular Aerosol Bioparox. often prescribed by doctors to treat upper respiratory tract infections, has suddenly been banned worldwide. Roszdravnazdzor has banned selling the drug since April 2016.

So why Bioparox, considered an effective antibiotic for decades, suddenly banned in Russia? The answer lies in the identified qualities of the main medicinal substance of Bioparox - physiophungine.


Bioparox - what is it and what is it used for?

Bioparox photo

Bioparox photo

Bioparox is an antibacterial aerosol used topically for bacterial damage of the upper respiratory tract. The basis of the drug - the polypeptide substance fusafungin (fusafunjin) - isolated from the fungus that infects cereals.

The discovery of Fusafunjina in 1963, which has a broad anti-bacterial spectrum against nasopharyngeal infection (streptococcus, pneumococcus, staphylococcus, Candida mushrooms, Mycoplasma pneumonia, some types of anaerobes and neuserium strains) was considered a revolutionary breakthrough in ENT practice.

The production of Bioparox by the French company Laboratories Servier quickly gained momentum, and the head of the pharmaceutical company Jacques Servier considered the drug to be his own pride.

From what used Bioparox, known to almost everyone. The drug was actively prescribed by doctors all over the world for the following diseases:

  • rhinitis and sinusitis;
  • pharyngitis / laryngitis;
  • tonsillitis (tonsillitis), including conditions after tonsillectomy.

In the course of preliminary studies, the drug Bioparox revealed the following unique properties:

  • anti-inflammatory effect develops due to a decrease in tumor necrosis factor (TNF-a); inhibition of the synthesis of toxins by macrophages is not accompanied by a decrease in the function of phagocytosis;
  • pathogenic microorganisms can not adapt to fusafungin (there is no effect of resistance);
  • when applied locally, the drug enters the blood in a critically low concentration (less than 1 ng / ml), which means no effect on the internal organs and systems;
  • in the side effects of the manufacturer indicated only a small risk of an allergic reaction, like any other antibiotic.

Due to these properties, Bioparroks, in many cases, made it possible to cure a throat infection without systemic (oral, injectable) administration of other antibiotics. Even with severe sore throat, Bioparox reduced the length of treatment with systemic antimicrobials and accelerated recovery.

Although there have been no studies on the effects on the fetus in humans, animal studies have revealed the teratogenic and genotoxic effects of fizafungin. Therefore, Bioparox during pregnancy, as well as breastfeeding, was not recommended.

Why banned Bioparox in Russia?

Bioparox is banned in Russia

Aerosol Bioparox, literally bursting into the pharmaceutical market, did not remain without further attention of scientists. Further studies of the drug raised a number of serious problems to the surface:

  1. Over time, Bioparox showed less and less effectiveness;
  2. The potential risk of developing resistance to other antibacterial substances has been identified;
  3. Side effects indicated by the manufacturer occur quite often and are more pronounced - from bronchospasm to anaphylactic shock.

In Russia in August 2015, the first restriction on the use of Bioparox was introduced. From now on, Bioparox in children was forbidden to use from 2.5 years, moving the age bar to 12 years. This change was immediately reflected in the instructions for the aerosol.

In the same year, the Italian organization AIFA, which regulates the circulation of medicines, appealed to the European Medical Agency in order to identify the frequent development of anaphylactic life-threatening shock.

At the same time, serious conditions developed after the use of Bioparox in both children and adult patients. One death was also reported. In 2016, in February, it was decided that Bioparox, although rare, could cause life-threatening reactions, effective measures for the prevention of which do not yet exist.

  • After that, Bioparox was removed from production, and the manufacturing company officially withdrawn the aerosol from the pharmaceutical market worldwide.

How to replace Bioparox? Analogs of the drug

It is the ratio of efficiency and safety that led to the removal of Bioparox from production and the ban in Russia in particular. Although today's pharmaceuticals offer a huge amount of local antiseptics and antibiotics, no other preparation can give a fine dispersion, like in Bioparox,. However, this aerosol can be replaced. Safer and cheaper Bioparox analogues:

Faringosept is an antiseptic; when tablets are resorbed, a bacteriostatic effect develops in the mouth (stops the growth of bacteria, and does not destroy them). Faringosept is effective when used immediately after the first symptoms of inflammation appear (tickling, redness, etc.). When an infection develops, it is used as a symptomatic remedy for reducing pain and relieving the inflammatory response.

Geksoral is an antiseptic (not an antibiotic!), Therefore its effectiveness is somewhat lower, and its use is necessarily combined with the intake of an antibacterial agent. Additionally has analgesic and antifungal effects.

Grammidine is an antibiotic that has a detrimental effect on a huge number of pathogenic microorganisms. Tablets for sucking cause abundant salivation, which helps to remove bacteria and toxic products of their vital activity from the oral cavity.

Tantum Verde - anti-inflammatory agent in the form of a solution and lozenges .

Polydex - a combined drug for nasal use, used exclusively for otitis and rhinitis. Although highly effective, its use is limited, as part of the glucocorticosteroid Dexamethasone.

Isofra - by its properties replaces the drug Bioparox. It has an antiseptic and antimicrobial effect, does not develop resistance in microorganisms.

Chlorophyllite is a herbal preparation that sets it apart from other local antiseptics. Isolated from the leaves of eucalyptus, a combination of chlorophylls has anti-inflammatory and antimicrobial action.

Based on the specificity of the infection of the nasopharynx, it is possible to choose a drug that can replace Bioparox. However, it should be remembered: any use of the antibiotic should be agreed with the doctor.

Even local antiseptics have a number of contraindications and side effects, and their therapeutic effect is not always sufficient for the treatment of respiratory diseases.

2016-11-14 08:31:16
Banning bioparox is simply a conspiracy by pharmaceutical companies, no other way! All drugs have side effects, and that someone took him "until blue in the face" is not a reason to prohibit. So aspirin can be poisoned ...
2016-12-10 10:46:34
There are no analogues! Now it is necessary to have systemic antibiotics - where is the justice ????? Need to organize a petition.
2016-12-21 08:11:57
So that France resumes release? :)
2016-12-22 12:28:45
Bioparox always helped me, and all my friends. Everyone advises him to everyone. I would call it a miracle cure. As soon as her throat ached, she always used. 3 days of use, sore throat goes away. and Maxillary treated them too. My body responds well to it. He does not cause any addiction, some kind of lie.
2016-12-22 12:31:00
Soon we will be treated with one chamomile.
2016-12-30 07:33:48
Tantum Verde does not help at all, return bioparox!
2017-02-06 09:28:37
Return Bioparox !!!!!
2017-02-22 17:36:44
Recover Bioparox
2017-02-24 00:06:05
Why would the servier not order the same test for the tantum verde who drove it out? Ugliness of course. The drug is indispensable. Sinusitis and generally severe colds have always treated.
2017-02-28 03:49:11
This is just a deal !!! Return Bioparox !!! No more analogues in the world. I was now overdue, and still helped!
2017-03-19 06:23:30
A good drug was 'Collusion 100 pounds'
2017-03-20 14:46:36
Not once bought this drug. And, to be honest, he absolutely did not help me and my children.
2017-03-22 09:29:56
Laryngitis cured in two days! Some kind of nonsense about the reason for the ban, a very effective drug. Half of the drugs in the back was written "anaphylactic shock." NO, it was Bioparox that was banned ((RETURN BIOPAROX !!)
2017-03-27 04:16:20
My child had a terrible allergy to him.
2017-04-03 19:32:29
Return Bioparox! This is just a stick - brace!
2017-04-11 16:23:39
RETURN BIOPAROX !!!!!!! The only antibiotic in aerosols with fine dispersion that could be inhaled and Biparox treated the tracheobronchitis! Instantly treated without side effects and in 3 days! intestinal tract and immunity! when you return Bioparox? Rather, return !!! people just turn into chronically sick and the children just puncture the maxillary sinuses for shimi many times, cough for half a year, suffer! And before that, Bioparosk and 3 days and all from strength 5 days and everything is healthy! Return !!!!!!!
2017-04-30 00:00:42
yes to the banal Nazivin, there can be both Quincke's edema and anaphylaxis, and this is not uncommon. However, do not prohibit him. A Bioparox banned for some reason. In most drugs there is an indication of the likelihood of allergic reactions, including anaphylactic shock. All have individual sensitivity. Someone will lick tomato and anaphylaxis will give out, but this does not mean that tomato is poison. Return Bioparox, a good drug was.
Kostya Belgorod
2017-04-30 16:43:12
I read the reviews and agree 100% that helped very well. 3 years in a row lay with bronchitis every year. As first used bioparoks cured in 3-5 days. For 8 years I forgot what is bronchitis. now I don’t know what to do and where to buy it .. I don’t want to eat tablets and prick the month in the old manner (((((
Dave gahan
2017-05-26 12:54:15
cured them of severe sinusitis, without any punctures and torment, just competitors crushed the manufacturer ((
Marina Shtepeleva (Komarova)
2017-07-18 05:02:03
I was very well helped by Bioparox. Prior to that, she had bronchitis three times a year for two or three months and terrible thrush and allergies from antibiotics. BRED DOGS WHAT BIOPAROX ALLERGENEN. ALLERGY NOW IN ANY WAS AND IS WITHOUT IT. TENDER COMPETITION OF PHARMACEUTICS.
2017-09-21 04:59:11
I agree completely! About people who really helps the drug no one thinks at all. Unfortunately, this commerce supplants what is needed and is checked by time.) Something must be done to get the drug back to the consumer market!
2017-09-27 05:25:34
Bioparox ideal for the treatment of bronchi and trachea. Used many times over 20 years. With proper inhalation, it reaches the lungs, which made it possible to quickly cure even the pulmonary mycoplasma, which other medicines could not cope with. It is possible to use for the throat, but infrequently - it dries the mucous membrane. It is for this reason that a negative opinion about the drug. But it should not be used for the upper, but for the lower respiratory tract, where other sprays, rinse solutions and throat resorption tablets cannot reach. For these cases, it is indispensable. Other antibiotics have much more severe side effects - from the death of the intestinal microflora (all antibiotics) to hearing loss (70% of antibiotics, including Isofra). NSAIDs, including aspirin, cause ulcers in the digestive tract with internal bleeding and death, which is written in each instruction. But they are not prohibited.
2017-09-28 05:51:25
very good drug
2017-10-04 05:10:04
It is a pity that Bioparox is no longer produced. I do not know what kind of allergies there are and who had them, maybe for those for whom a little discomfort is more important than undoubted benefit. Fine was a remedy, practically saved from the removal of the glands. I did not find a similar replacement in quality and efficiency.
2017-10-17 05:36:31
Of course, now this trend - all that really treats, withdraw from sale, simple wrecking and even competition from pharmacists
Yuri Rodionov
2017-11-07 08:03:52
Pharmacists around the world is EVIL!
2017-11-13 09:38:16
Destruction of the effective drug Bioparox for the sake of expensive temporarily soothing dummies such as Imudon, in order to earn money on people's health, no matter what!
2017-12-05 05:21:03
Bastards, want more patients to produce, that they sucked their immudons and strepsils, dragged the loot to freaks. Return an effective drug. And sympathetic suckers, shove yourself .... where they fit together.
2017-12-07 06:33:55
so they died, who forbade him
2018-01-09 09:02:50
now there is a struggle for "only a doctor can prescribe an antibiotic." A correct antibiotic can be assigned only after analysis on the microflora. 5 days or more is done. and only paid. because free of charge in the clinic do not detect any microflora.
Angelica Makovetskaya
2018-01-18 05:04:38
as always effective prohibit prevented other nonsense to sell
2018-02-19 07:22:47
Now all children with bronchitis have been put on hormones - Pulmicort and Berodual and Atrovent, is it really not harmful?

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